sklb 610 Search Results


sklb 610  (TargetMol)
96
TargetMol sklb 610
Sklb 610, supplied by TargetMol, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sklb 610/product/TargetMol
Average 96 stars, based on 1 article reviews
sklb 610 - by Bioz Stars, 2026-04
96/100 stars
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sklb610 s6526  (Selleck Chemicals)
91
Selleck Chemicals sklb610 s6526
The IC 50 values of four anticancer agents in human lung cancer cells.
Sklb610 S6526, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sklb610 s6526/product/Selleck Chemicals
Average 91 stars, based on 1 article reviews
sklb610 s6526 - by Bioz Stars, 2026-04
91/100 stars
  Buy from Supplier

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The IC 50 values of four anticancer agents in human lung cancer cells.

Journal: International Journal of Molecular Sciences

Article Title: Cytochrome P450 27C1 Level Dictates Lung Cancer Tumorigenicity and Sensitivity towards Multiple Anticancer Agents and Its Potential Interplay with the IGF-1R/Akt/p53 Signaling Pathway

doi: 10.3390/ijms23147853

Figure Lengend Snippet: The IC 50 values of four anticancer agents in human lung cancer cells.

Article Snippet: Anticancer agents, vinorelbine ditartrate (S4269), picropodophyllin (S7668), pacritinib (S8057), and SKLB610 (S6526) were obtained from Selleck Chemicals (Houston, TX, USA).

Techniques:

CYP27C1-knockdown attenuates anticancer potency of protein kinase inhibitors. ( A – E ) A549-shCYP27C1, H1975-shCYP27C1, and the corresponding control cells were treated with indicated concentration of protein kinase inhibitors (picropodophyllin, pacritinib, and SKLB610). Real-time cell index reflecting cell viability were detected by RTCA-S16 System. Results were analyzed by two-way ANOVA. ****, p <0.0001, **, p <0.01, *, p < 0.05, n.s., p > 0.05. ( F ) Stable CYP27C1-knockdown H1975 cells and the corresponding control cells were treated with indicated concentrations of SKLB610, cell viability was determined by MTS assay at different time point, and analyzed by two-way ANOVA. ****, p <0.0001.

Journal: International Journal of Molecular Sciences

Article Title: Cytochrome P450 27C1 Level Dictates Lung Cancer Tumorigenicity and Sensitivity towards Multiple Anticancer Agents and Its Potential Interplay with the IGF-1R/Akt/p53 Signaling Pathway

doi: 10.3390/ijms23147853

Figure Lengend Snippet: CYP27C1-knockdown attenuates anticancer potency of protein kinase inhibitors. ( A – E ) A549-shCYP27C1, H1975-shCYP27C1, and the corresponding control cells were treated with indicated concentration of protein kinase inhibitors (picropodophyllin, pacritinib, and SKLB610). Real-time cell index reflecting cell viability were detected by RTCA-S16 System. Results were analyzed by two-way ANOVA. ****, p <0.0001, **, p <0.01, *, p < 0.05, n.s., p > 0.05. ( F ) Stable CYP27C1-knockdown H1975 cells and the corresponding control cells were treated with indicated concentrations of SKLB610, cell viability was determined by MTS assay at different time point, and analyzed by two-way ANOVA. ****, p <0.0001.

Article Snippet: Anticancer agents, vinorelbine ditartrate (S4269), picropodophyllin (S7668), pacritinib (S8057), and SKLB610 (S6526) were obtained from Selleck Chemicals (Houston, TX, USA).

Techniques: Knockdown, Control, Concentration Assay, MTS Assay